Stepwise Normalization of Two-Channel Spotted Microarrays
نویسندگان
چکیده
منابع مشابه
Appendix: Normalization of Two-Channel Microarrays Accounting for Experimental Design and Intensity-Dependent Relationships
Translating the eCADS model While we do not know the x il , we are able to estimate monotone-increasing functions of them, as follows. Let x * il = d(x il) = (d(x il) + δ 1 (x il) + d(x il) + δ 2 (x il))/2. Now define functions d * , δ * k , and a * d * (x * il) = x * il = d(x il) δ * k (x * il) = δ k (x il) a * j (x * il) = a j (x il). The new dye functions d * (x * il) + δ * k (x * il) are al...
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ژورنال
عنوان ژورنال: Statistical Applications in Genetics and Molecular Biology
سال: 2005
ISSN: 1544-6115,2194-6302
DOI: 10.2202/1544-6115.1117